Health Condition 1: K049- Other and unspecified diseases ofpulp and periapical tissues Health Condition 2: K084- Partial loss of teeth
Conditions
Interventions
Intervention1: Concentrated growth factor (CGF): immediate implant will be placed with platelet concentrate obtained from autlogous blood, immediately centrifuged at different speeds 2700 rpm for 4 m
Sponsors
All India Institute of Medical Sciences Jodhpur Basni AIIMS Jodhpur Rajasthan
Eligibility
Inclusion criteria
Inclusion criteria: 1. Adult Patients of either sex (age-18 -65 yrs.) 2. Non restorable maxillary or mandibular molar teeth requiring extraction. 3. Presence of adequate amount of bone after extraction 4. Patients with good oral hygiene
Exclusion criteria
Exclusion criteria: 1. Presence of uncontrolled systemic or local diseases preventing dental implants. 2. Patients having bleeding disorder 3. The need for additional bone augmentation procedures (such as maxillary sinus augmentation, distraction osteogenesis) 4. Patients allergic to any of the material used during procedure 5. Presence of local infection/ extensive bone loss 6. Pregnant females, smokers 7. Patients under medications that interfere with bone metabolism and gingival tissue health. 8. Patients taking any drug known to affect the number or function of platelets in the past 3 months. 9. Patients with abnormal platelet counts.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the stability of immediately placed dental implants in maxillary and mandibular molar region with CGF and PRF using RFA.Timepoint: 0, 4 week, 8 week, 12/16 week | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To evaluate the bone regenerate around implant with the use of PRF and CGF 2. To quantify growth factors VEGF and TGF β1 in prepared CGF and PRF and its correlation with bone healing. Timepoint: 0, 4 week, 8 week, 12/16 week | — |
Countries
India
Contacts
Public ContactDr Shubham
AIIMS Jodhpur
Outcome results
None listed