Comparison of pain relief and safety of doing a nerve blcok versus injection of local anaesthetics at surgical site in patients undergoing video assisted thoracic surgery

COMPARISON OF ANALGESIC EFFICACY AND SAFETY OF ERECTOR SPINAE PLANE BLOCK VERSUS LOCAL INFILTRATION IN VIDEO ASSISTED THORACOSCOPIC SURGERY IN ADULT PATIENTS

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/10/015914

Enrollment

Registered

2018-10-05

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J852- Abscess of lung without pneumonia Health Condition 2: O- Medical and Surgical Health Condition 3: G700- Myasthenia gravis

Interventions

Intervention1: Erector Spinae Plane Block: Ultra sound guided erector spinae plane block with 0.375% ropivacaine with adrenaline 5 microgram/ml Control Intervention1: Local Infiltration: 20 ml of 0.37

Eligibility

Inclusion criteria

Inclusion criteria: ASA I OR II Patients scheduled for VATS

Exclusion criteria

Exclusion criteria: Patient refusal Known allergy to local anesthetics Bleeding diathesis Patients suffering from chronic pain Inability to operate PCA pump

Design outcomes

Primary

Measure	Time frame
VAS score for pain and total analgesic requirementTimepoint: VAS (visual analogue scale) score at rest and during movement is assessed at 0, 2, 4, 6, 8, 12, 24 hours after surgery. All patients are given PCA morphine pump after ensuring a VAS of less than 4 with the use of morphine 3mg iv bolus. PCA will be provided with 1 mg morphine bolus with a lock out time of 10 minutes,allowing a maximum dose of 20mg in 4 hours.The time taken for the first use of PCA is noted. PCA morphine consumption is assessed at the end of 6 12 and 24 hours.	—

Measure

Time frame

VAS score for pain and total analgesic requirementTimepoint: VAS (visual analogue scale) score at rest and during movement is assessed at 0, 2, 4, 6, 8, 12, 24 hours after surgery. All patients are given PCA morphine pump after ensuring a VAS of less than 4 with the use of morphine 3mg iv bolus. PCA will be provided with 1 mg morphine bolus with a lock out time of 10 minutes,allowing a maximum dose of 20mg in 4 hours.The time taken for the first use of PCA is noted. PCA morphine consumption is assessed at the end of 6 12 and 24 hours.

—

Secondary

Measure	Time frame
Incidence of side effects- PONV, pruritis, neurological sequelae,local side effects, respiratory depressionTimepoint: 24 hours;Intraoperative hemodynamics and blood lossTimepoint: Intraoperative;Overall patient satisfaction for pain managementTimepoint: 24 hours	—

Countries

India

Contacts

Public ContactDr Lokesh Kashyap

All India Institute Of Medical Sciences,New Delhi

lokeshkashyap@yahoo.com9873531192

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026