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To assess whether a hormone called leptin which maintains healthy weightloss and increases energy expenditure is altered and to see how a 12 weeks physical activity program helps in regulating abnormal increase in leptin which is called leptin resistance in individuals with metabolic syndrome

effect of physical activity promotion program on leptin resistance and quality of life among people with metabolic syndrome

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/10/015885
Enrollment
160
Registered
2018-10-03
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E889- Metabolic disorder, unspecified

Interventions

Intervention1: PHYSICAL ACTIVITY PROMOTION PROGRAM: Participants will be given a 12 week physical activity promotion program consisting of 150 minutes of moderate-intensity physical activity throughou

Sponsors

World diabetes foundation WDF
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Participants with age group above 30 years to 50 years, either gender are included in the study. Participants will be included on the basis of metabolic syndrome parameters like waist circumference >94cm for males and >80cm for females, BMI >25kg/m2, fasting blood glucose >100mg/dl, blood pressure >130/85mmhg, serum triglycerides >150mg/dl, HDL 9.5ng/ml for males >25.0ng/ml for females, sedentary lifestyle according to GPAQ screening

Exclusion criteria

Exclusion criteria: History of smoking past 6 months, Cardiovascular disease, Stroke, TIA, Any cognitive impairment, Any recent surgeries which hinder with physical activity, Systemic illness

Design outcomes

Primary

MeasureTime frame
Serum Leptin, Metabolic parameters ( lipid profile, fasting blood glucose, waist circumference), Quality of life ââ?¬â?? WHOQOL- BREF, GPAQ Timepoint: 3 time points 1.pre-intervention -Serum Leptin, Metabolic parameters ( lipid profile, fasting blood glucose, waist circumference), Quality of life ââ?¬â?? WHOQOL- BREF, GPAQ 2. post intervention (12 weeks) - all the primary outcomes 3. At the end of 3 months follow up post interventon- Metabolic parameters ( lipid profile, fasting blood glucose, waist circumference), Quality of life ââ?¬â?? WHOQOL- BREF, GPAQ—

Secondary

MeasureTime frame
Body composition, BMR Homocysteine, Fasting Insulin Timepoint: Participants will be followed up for 3months and all the primary and secondary outcomes are assessed. Quality of life will be assessed using WHOQOL BREF questionnaire. Additional parameters like homocysteine and fasting insulin will be assessed pre and post intervention—

Countries

India

Contacts

Public ContactParameshwar A

School of Allied Health Sciences, Manipal Academy of Higher Education

param.anche@gmail.com9686382612

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026