To compare the effects of magnesium sulphate and low dose of dexmedetomidine on pulse, BP of patients undergoing laparoscopic cholecystectomy under anaesthesia.

Comparative evaluation of effects of magnesium sulphate and low dose of dexmedetomidine on haemodynamic parameters in patients undergoing laparoscopic cholecystectomy under general anaesthesia.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/09/015841

Enrollment

Registered

2018-09-26

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z69-Z76- Persons encountering health services in other circumstances

Interventions

Intervention1: 50mg/kg magnesium sulphate 0.5micrograms/kg dexmedetomidine intravenously in 100 ml NS over 10 min.: Drug is given over 10min in 100ml NS after induction of anesthesia but before creati

Eligibility

Inclusion criteria

Inclusion criteria: Patients scheduled for elective laparoscopic cholecystectomy under general anaesthesia. Aged between 18-60yrs. Belonging to ASA1.

Exclusion criteria

Exclusion criteria: History of cardiovascular diseases like hypertension, ischaemic heart disease,conduction defects etc. History of compromised renal/hepatic/neuronal functions. Pregnant/lactating women Endocrine diseases eg. Diabetes mellitus,hyper and hypothyroidism. Patient on any drug affecting cardiovascular parameters eg.CCB,beta blockers, magnesium sulphate etc.

Design outcomes

Primary

Measure	Time frame
To compare SBP in patients of two groups during pneumoperitoneumTimepoint: To compare SBP in patients of two groups during pneumoperitoneum pre induction,just after induction at 1 and 3 min,post induction, during pneumoperitoneum at interval of 10 minutes,after desufflation and after extubation.	—

Secondary

Measure	Time frame
To compare HR, DBP and MAP during pneumoperitoneumTimepoint: Preinduction,after induction,and post intubation at 1,3 min, before pneumoperitoneum, during pneumoperitoneum at interval of 10 minutes,before desufflation,after desufflation,and after extubation.	—

Countries

India

Contacts

Public ContactHina Faraz

University college of medical sciences and guru teg bahadur hospital, shahadra, Delhi 95.

hina.faraz92@gmail.com8826828467

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026