Health Condition 1: E039- Hypothyroidism, unspecified Health Condition 2: E039- Hypothyroidism, unspecified
Conditions
Interventions
Intervention1: Levothyroxine morning dose: levothroxine tablet will be given according to biochemical parameters and body weight.
Control Intervention1: Levothyroxine evening dose: Efficacy of levothr
Sponsors
DIPAN SAHA
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients with primary hypothyroidism, who are drug naïve.
Exclusion criteria
Exclusion criteria: 1.Patients who are already on levothyroxine therapy. 2. Seriously ill patients (such as malignancy etc.) 3. Patients with serious infective diseases (such as TB, AIDS etc.) 4.Pregnant and lactating mothers. 5.Known liver disease, chronic obstructive pulmonary disease and chronic renal disease. 6. Patients on medications (e.g. iron, calcium, proton pump inhibitor, amiodarone, etc) which can interfere with levothyroxine absorption or have an effect on thyroid profile.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum T3, T4 and TSH levels Adverse drug reactionTimepoint: baseline, after 8 weeks and after 24 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| lipid profile , plasma glucoseTimepoint: baseline, after 8 weeks and after 24 weeks | — |
Countries
India
Contacts
Public ContactDr Dipan Saha
Midnapore Medical College
Outcome results
None listed