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A study to compare the improvement of hand function in patients suffering from Rheumatoid Arthritis by injecting Depot Methyl Prednisolone either in joints or in muscles.

Comparison between intraarticular versus intramuscular Depot Methyl Prednisolone administration in functional improvement of hand in patients suffering from Rheumatoid Arthritis.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/09/015765
Enrollment
62
Registered
2018-09-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients suffering from Rheumatoid Arthritis for less than 2 years.

Interventions

Intervention1: Injection Depot Methyl Prednisolone (40mg/ml) intramuscularly: Patients in IM group were given intramuscular (IM) depot methyl prednisolone injection (40mg) in the gluteal region on the

Sponsors

Institute Of Post Graduate Medical Education And Research SSKM Hospital Kolkata
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Diagnosis of Rheumatoid Arthritis as per ACR/EULAR 2010 classification criteria 2. One or more inflamed joints of hand 3. Duration of disease- less than 2 years

Exclusion criteria

Exclusion criteria: 1. Already deformed joints 2. Uncontrolled Diabetes, hypertension, bleeding diathesis, h/o leprosy, any other neuropathic disorder 3. Associated fracture or traumatic injury to tendons 4. Open wound or local skin infection 5. Overlap syndromes 6. Who have received intra-articular steroid earlier or is on systemic steroid at time of presentation.

Design outcomes

Primary

MeasureTime frame
Patientâ??s disease activity assessment by Clinical Disease Activity Index (CDAI). (0.0-2.8)Timepoint: Patientâ??s disease activity assessment by Clinical Disease Activity Index (CDAI). (0.0-2.8):3 months—

Secondary

MeasureTime frame
1. Range of motion of joints. 2. Hand grip measurements. 3. Patientâ??s disease activity assessment by Clinical Disease Activity Index (CDAI). (0.0-2.8) 4. Hand function assessment using Keitel Functional Test. ( parameters 1 to 9)Timepoint: 1. Range of motion of joints:1 month,3 months 2. Hand grip measurements:1 month,3 months 3. Patientâ??s disease activity assessment by Clinical Disease Activity Index (CDAI). (0.0-2.8):1 month 4. Hand function assessment using Keitel Functional Test. ( parameters 1 to 9):1 month,3 months—

Countries

India

Contacts

Public ContactProfDr RNHaldar

Calcutta National Medical College,Kolkata

drswarnlimndl@gmail.com9433818972

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026