Health Condition 1: null- Stable: ASA grade 1 &2
Conditions
Interventions
Intervention1: Ropivacaine with Nalbuphine
: Ropivacaine with saline Versus Ropivacaine with Nalbuphine. Ropivacaine with saline to act as control, to give analgesia to all patients involved in trial.
Sponsors
AIIMS Rishikesh
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged 18-60 years of either sex 2) Belonging to ASA physical status I and II 3) Planned for laparoscopic cholecystectomy 4) Patients without cognitive impairment or mental retardation. 5) Free from pain in preoperative period.
Exclusion criteria
Exclusion criteria: Exclusion criteria 1) Refusal by patient for any reason 2) Conversion of laparoscopic approach to open surgery 3) History of alcohol or drug addiction 4) Severe hepatic or renal impairment 5) Allergy to the study drugs 6) Patients with communication problems, cognitive impairment 7) Pregnancy or lactation 8) Chronic pain treatment 9) Anti-epileptic therapy (to avoid confusion with seizures as part of LAST- local anaesthetic systemic toxicity) 10) Patients below 18 years or above 60 years of age
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Compare the effectiveness on the basis of visual analog pain scale, of intraperitoneally administered: Ropivacaine alone against Ropivacaine with NalbuphineTimepoint: 2 years | — |
Secondary
| Measure | Time frame |
|---|---|
| To know the extent of systemic absorption of the drugs administered intraperitoneally, assessed by serum levels of respective drugs. To know and compare the incidence and severity of complications of each drug used.Timepoint: 2 years | — |
Countries
India
Contacts
Public ContactAbullais Raheeq Gowda
AIIMS Rishikesh
Outcome results
None listed