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Study of different vasopressors for hypotention after spinal anaesthesia in Lower Section Caesarean Section(LSCS)

A comparison between ephedrine and phenylephrine injection for the treatment of hypotention in Lower Segment Caesarean Section during Subarachnoid block (spinal anaesthesia).

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/09/015750
Enrollment
100
Registered
2018-09-18
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- american society of anaesiology (ASA ) class 1 and class 2 parients who posted in operation theatre for lower section caeserian section under spinal anaesthesia

Interventions

Intervention1: injEphedrine, injPhenylephrine: 1)Ephedrine has both indirect and direct actions on the sympathetic nervous system. Its indirect effects are due to the stimulation of postganglionic sym

Sponsors

Government Medical Collage Surat
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)ASA Grade 1 and 2 2)Age 18 to 30 years 3)Patients with valid consent (informed and written) 4)Full term parturients with Singleton pregnancy posted for emergency/elective caesarean section under spinal anesthesia

Exclusion criteria

Exclusion criteria: 1)ASA grade III/IV patient 2)Contraindications to regional anesthesia 3)Hypersensitivity to the study drugs 4)Parturients taking tricyclic antidepressants and MAO inhibitors, because phenylephrine is contraindicated in these cases 5)Parturients with hypertension (BP >=160/90) (PIH/HTN), cardio-vascular diseases, hyperthyroidism, atherosclerosis, bronchial asthm

Design outcomes

Primary

MeasureTime frame
This study is designed to comparatively evaluate the effects of phenylephrine and ephedrine used in treatment of spinal anaesthesia induced hypotension in patients undergoing LSCS.Timepoint: Intra-operation i will monitor pulse, blood pressure and any complication at every 2 minutes after giving these medication whenever hyphenation develops.

Secondary

MeasureTime frame
If these vasopressureS will be given before the delivery of baby, we will monitor newborn baby for vitals(pulse)and APGAR score with effects in mother.Timepoint: We will monitor pulse and APGAR score of every newborn just after delivery and then once after 5 minutes.Intra and post operation we will look for any side effects in mother.

Countries

India

Contacts

Public ContactDhavalkumar C Patel

Government Medical College Surat

dcp991717@gmail.com9898866862

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026