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A clinical trial to evaluate the effect of 2 different methods of oxygen supplementation in preventing fall in oxygen saturation during intubation in ICU

Peri-intubation oxygenation techniques to minimize the degree of hypoxia in patients with hypoxemic respiratory failure in intensive care unit.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/09/015747
Enrollment
60
Registered
2018-09-18
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J40-J47- Chronic lower respiratory diseases Health Condition 2: J09-J18- Influenza and pneumonia Health Condition 3: J95-J95- Intraoperative and postprocedural complications and disorders of respiratory system, not elsewhere classified Health Condition 4: J20-J22- Other acute lower respiratory infections

Interventions

Intervention1: Nasopharyngeal Airway Group: Apneic oxygenation along with Continuous positive airway pressure(CPAP) delivered through Nasophayngeal airway during intubation of hypoxix patients in ICU

Sponsors

Sri Devaraj Urs Academy of Higher Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with Type I (Hypoxemic) respiratory failure, without any hemodynamic compromise. Hypoxemic respiratory failure is defined as respiratory rate > 30 breaths/min and an FiO2 requirement of 50% or more to obtain oxygen saturation of at least 90%, and PaO2 to FiO2 ratio below 300 mmHg, in the 4 hours before inclusion. Hemodynamic compromise is defined as MAP

Exclusion criteria

Exclusion criteria: 1.Patients with anticipated difficult airway as evaluated using MACOCHA score 2.Pregnant or breast feeding woman 3.Contraindications to nasopharyngeal airway insertion like nasopharyngeal obstruction, coagulopathies etc.. 4.Contraindications to NIV such as patients with claustrophobia, full stomach and GCS 5.Contraindications to Ketamine and Succinylcholine such as raised intracranial tension, ischemic heart disease, hyperkalemia etc..

Design outcomes

Primary

MeasureTime frame
To compare CPAP through Nasopharyngeal airway with O2 through Nasal prongs as a mode of Peri-intubation oxygenation for reducing the degree of desaturation while intubating patients with hypoxemic respiratory failure in ICUTimepoint: 18 months—

Secondary

MeasureTime frame
: To assess the complications related to intubation of patients with hypoxemia in the ICU: 1. Degree of intubation difficulty as graded on IDS ( Intubation difficulty score) 2. Degree of hemodynamic compromise ( percentage change in HR & MAP) 3. Incidence of Bradycardia or tachyarrhythmiasTimepoint: 18 months—

Countries

India

Contacts

Public ContactSumanth T

SDUAHER, Kolar

tom2f4u@gmail.com9535974751

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 9, 2026