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Incidence and risk factors related to meningitis ocuring after neurosurgical operation

Incidence of post-operative meningitis, risk factor and antibiotic sensitivity in neurosurgical patients: An institutional audit.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/09/015743
Enrollment
200
Registered
2018-09-18
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B95-B97- Bacterial and viral infectious agents Health Condition 2: A498- Other bacterial infections of unspecified site

Interventions

Intervention1: NIL: NIL

Sponsors

Shilpa Sundar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.All post-operative patients [including all craniotomies (both tumor and trauma), endonasal procedures, procedures involving placement of implants or drains] under the Department of Neurosurgery who have been newly diagnosed with meningitis confirmed by CSF cultures and biochemical investigations, 2.Patients who develop infection within 30 days of primary surgery 3.Patients who have survived for more than 72 hoursâ?? post-surgery, 4.Patients who have undergone a redo surgery because of a direct cause or result of the primary surgery, within 30 days from the primary surgery.

Exclusion criteria

Exclusion criteria: 1.Patients who underwent surgery outside the institution (Department of Neurosurgery, Kasturba Hospital, Manipal), 2.Patients who develop infection after 30 days of primary surgery, 3.Patients below 18 years of age, 4.Patients diagnosed with non-CNS infection prior to primary surgery, 5.Patients without positive CSF culture and biochemical investigations.

Design outcomes

Primary

MeasureTime frame
Study exposure variables: Glasgow Coma Scale (GCS), CSF studies â?? culture reports and biochemical profile, Neuro imaging â?? CT Brain (Plain and contrast) and MRI Brain, Antibiotic spectrum. Study Outcome Variables: Drop in GCS, focal or diffuse neurological deficit, seizures and any form of neurological obtundation post-surgery ; Setting up a microbiological spectrum and Antibiotic protocol for postoperative neurosurgical patients with meningitis.Timepoint: at the end of follow up of each patient

Secondary

MeasureTime frame
Make a protocol for management of post operative meningitis for this institutionTimepoint: till follow up

Countries

India

Contacts

Public ContactRajesh Nair

Manipal Academy Of Higher Education

shlpasundar1214@gmail.com7204289228

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026