Health Condition 1: V00-Y99- External causes of morbidity
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Gingival Index (GI) >1; Probing Depth (PD) > 5mm and Clinical Attachment Loss (CAL) > 3mm with alveolar bone loss affecting > 30% of the teeth as detected on radiograph at the time of initial diagnosis, based on the classification by American Academy of Periodontology, 1999.
Exclusion criteria
Exclusion criteria: 1. Patients with medical disorders such as cardiovascular or renal disease, etc. 2. Patients with recent history or presence of acute or chronic infection. 3. Individuals with history of tobacco chewing and smoking. 4. Pregnant and lactating females. 5. Patients with history of periodontal therapy or antibiotic treatment or any other anti-inflammatory medication within previous 6 months. 6. Patients with history of poorly controlled diabetes, liver diseases, malignancy, radiotherapy, or allergy to toluidine blue.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in GCF levels of Interleukin-6, Interleukin-8, and Interleukin-10 are evaluated in chronic periodontitis patients undergoing Non-Surgical Periodontal therapy along with Photodynamic therapy in 3 months.Timepoint: 3 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in periodontal status i.e reduction in probing pocket depth and gain in clinical attachment level in chronic periodontitis patients undergoing Non-Surgical Periodontal therapy along with Photodynamic therapy at 1 and 3 monthsTimepoint: 3 months | — |
Countries
India
Contacts
VSPM Dental College & Research Centre, Nagpur