Health Condition 1: K55-K64- Other diseases of intestines
Conditions
Interventions
None listed
Sponsors
Syed Nusrath
Ajesh Saksena
KVVN Raju
Pratap Reddy
Subramanyeshwar Rao
Sujith Chyau Patnaik
Eligibility
Inclusion criteria
Inclusion criteria: Biopsy-proven, primary, low rectal cancer of histology adenocarcinoma and no previous therapy for rectal cancer, Patient consenting. No organ failure
Exclusion criteria
Exclusion criteria: Patient not consenting, Current pregnancy, Previous pelvic/rectal malignancy, Previous pelvic radiotherapy, Previous pelvic surgeries especially for fecal incontinence or prolapse. General MRI contraindications -- Pregnancy, Implanted metal devices, Pacemakers, Cochlear implants, Artificial cardiac valves, Claustrophobia or cardio-pulmonary dysfunction patients who are unable to tolerate a MRI.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To validate high resolution MRI staging system in lower rectal cancer by defining the tumor-mesorectal fascia relation-ship and to guide the treatment planningTimepoint: 18 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Analysis of different clinical and radiological factors involving the decision making by surgeons to carry out Anterior Resections, Abdomino-perineal resections or extralevator abdomino-perineal resection. Timepoint: 18 months;Comparison of MRI imaging and pathology staging assessment between different types of surgical approaches. Timepoint: 18 months;Evaluation of potential associations between imaging and pathology assessment of radial and distal margins, neo-adjuvant chemoradiotherapy, perineal complications and sphincter preservation ratesTimepoint: 18 months | — |
Countries
India
Contacts
Public ContactDr Subramanyeshwar Rao
Department of surgical oncology, 4th floor, New block, BIACHRI, Hyderabad
Outcome results
None listed