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To compare the effects of two drugs used in brachial plexus block in upper limb surgery

Comparative study between dexmedetomidine and dexamethasone adjuvant to levobupivacaine in ultrasound guided supraclavicular brachial plexus block scheduled for upper limb surgery

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/09/015694
Enrollment
60
Registered
2018-09-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S50-S59- Injuries to the elbow and forearm

Interventions

Intervention1: Dexmedetomidine: The use of clonidine, a partial α2 adrenoceptor agonist, in peripheral nerve blocks, has been reported to be safe and prolongs the duration of anaesthesia and analgesi

Sponsors

AIIMS Raipur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Sixty patients aged 18 to 60 years, ASA physical status Iâ??II, scheduled for upper limb and hand surgery under supraclavicular brachial plexus block with 0.5% levobupivacaine, will be recruited.

Exclusion criteria

Exclusion criteria: a) Patients with contraindications for brachial plexus block b) ASA grade III and above c) Known allergy to any of the study medications d) Acute or chronic respiratory disease e) Hypertension or Cardiovascular abnormalities f) Patients receiving adrenoceptor agonist or antagonist or chronic analgesic therapy g) Diabetes Mellitus

Design outcomes

Primary

MeasureTime frame
Onset time and Duration of Motor and Sensory blocks.Timepoint: Sensory and Motor blocks will be evaluated every 5 minutes until 20 minutes after injection, and then 30 min after surgery, until the block resolves.

Secondary

MeasureTime frame
Adverse events such as sedation, hypotension, bradycardiaTimepoint: HR, SBP, DBP and SpO2 will be recorded at 0 min, 1 min, 5 min, 10 min and then after every 10 min intervals during the surgery and then hourly for the next 24 hours

Countries

India

Contacts

Public ContactMonica Khetarpal

AIIMS, Raipur

monicakhetrapal@yahoo.com08518881714

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026