To study the effect of combination of dexamethasone and ropivacaine given in serratus anterior plane with the help of ultrasound in breast cancer surgery.

Effect of adding dexamethasone to ropivacaine on ultrasound guided serratus anterior plane block for modified radical mastectomy: A Prospective randomized controlled pilot study

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/09/015650

Enrollment

Registered

2018-09-07

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site Health Condition 2: null- Patient having breast cancer will be the participant in this trial

Interventions

Intervention1: Group D: Modified radical mastectomy under general anaesthesia along with SAP block using 0.375% Ropivacaine and 2 ml(8mg) Dexamethasone(total volume 0.4 ml/kg) Control Intervention1:

Eligibility

Inclusion criteria

Inclusion criteria: American society of anesthesiologistâ??s (ASA) physical status (PS) I and II Weight 30-80 kg

Exclusion criteria

Exclusion criteria: 1.Refusal of the patients to give informed consent 2.Preexisting coagulation disorders 3.Morbid obesity 4.Local infection at the site of the block 5.Allergy to the drug under study 6.Patient with severe chest wall deformity

Design outcomes

Primary

Measure	Time frame
Time to first rescue analgesia in the postoperative period in woman undergoing modified radical mastectomy under general anaesthesia with SAP Block with placebo and SAP block with dexamethasone.Timepoint: Within first 24 hours post MRM	—

Secondary

Measure	Time frame
Total fentanyl consumption during intraoperative period among the two groups. Total doses of diclofenac(75 mg) consumed in the post operative period in 24 hours. Total tramadol consumption(mg) in the post operative period in 24 hours. Occurrence of nausea and vomiting in post-operative period. Timepoint: Intraoperative and first 24 hours postoperative.	—

Countries

India

Contacts

Public ContactDr Vinod Kumar

AIIMS

vkchanpadia@gmail.com01129575106

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026