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Comparison of clinical effects of Achyranthes aspera Gel And Tetracycline Fibres as local drug delivery in chronic periodontitis patients

Comparative Clinical Evaluation Of The Efficacy Of Local Drug Delivery Of Achyranthes aspera Gel And Tetracycline Fibres In The Management Of Chronic Periodontitis Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/09/015621
Enrollment
40
Registered
2018-09-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z008- Encounter for other general examination Health Condition 2: null- Systemically healthy patients, Age between 20-60 years with Chronic periodontitis with isolated periodontal pockets(greater than or equals to 5 mm) with minimum of 10 teeth in cooperative patients

Interventions

Intervention1: Achyranthes aspera Gel: Active components are Ecdysterone, Oleanolic acid,other new aliphatic acid identified as n-hexacos-14-enoic acid from the roots of the plant. Other compounds in

Sponsors

Dr Geetika Prabhakar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients in good systemic health. 2. The patients ranged in age from 20 to 60 years. 3. Patients with chronic periodontitis with isolated periodontal pockets. (probing pocket depths greater or equal to 5 mm) 4. Patients with a minimum of 10 teeth in their total dentition. 5. Cooperative patients who can be motivated to maintain good oral hygiene.

Exclusion criteria

Exclusion criteria: 1. Subjects who did not give consent. 2. Subjects using antibiotic medications, mouthwashes, chewing gums, tobacco at the time of the study or 6 months prior to it. 3. Patients with known hypersensitivity to Tetracycline 4. Patients with furcation involvement. 5. Subjects having any oral or systemic disease. 6. Pregnant and/or lactating mothers. 7. Patients with any bleeding disorders or on anticoagulant therapy. 8. Patients who had received any type of periodontal therapy for the past 6 months 9. Patients who were smokers or had tobacco in any other form.

Design outcomes

Primary

MeasureTime frame
Pathologic periodontal pockets in chronic periodontitis patients will be treated thereby eliminating the diseased condition, which is very important for periodontal and general health of patient.Timepoint: clinical parameters will be assessed at base line and after 3 months.

Secondary

MeasureTime frame
Pathologic periodontal pockets in chronic periodontitis patients will be treated thereby eliminating the diseased condition thus improving general health of patient.Timepoint: clinical parameters will be assessed at base line and after 3 months.

Countries

India

Contacts

Public ContactGeetika Prabhakar

Nair Hospital Dental College

maladixit25@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026