Health Condition 1: H40-H42- Glaucoma
Conditions
Interventions
None listed
Sponsors
To be submitted to Indian Funding Agency for Grant
Eligibility
Inclusion criteria
Inclusion criteria: Pre-operative Intraocular Pressure less than 18mmHg
Exclusion criteria
Exclusion criteria: a) Known cases of Primary and secondary Glaucoma/ Ocular hypertension except the Primary Open Angle Glaucoma groups. The Primary Open Angle Glaucoma groups should not have any other associated glaucomas. b) Known Asthmatics on treatment with any form of steroids. c) History of any recent intra-ocular intervention within 6 months from recruitment. d) Traumatic cataract, Mature and hyper mature cataract. e) Any Intra operative complications. (Like Posterior Capsular Rent, Zonular Dialysis etc.) f) Immediate post-operative complications requiring intervention. g) Any case of Uveitis. h) Taking any form of steroids for the last six months
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| to investigate the correlation between steroid responsiveness and GR alpha/beta ratio expression Timepoint: 24 months | — |
Primary
| Measure | Time frame |
|---|---|
| "1. To study the steroid-induced intraocular pressure response following phaco-emulsification 2. To estimate the ratio of GR alpha/beta mRNA expression in peripheral mononuclear cells (PBMC) from enrolled study patients by qPCR 3. To correlate the steroid responsiveness with GR alpha/beta ratio expression"Timepoint: Six Months | — |
Countries
India
Contacts
Public ContactDr Srilekha Pallamparthy
Aravind Medical Research Foundation
Outcome results
None listed