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Benefits of neem for Oral lichen planus patients.

Evaluation of the effectiveness of neem extracts mouthwash as an adjuvant therapeutic modality in the management of oral lichen planus

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/08/015563
Enrollment
45
Registered
2018-08-31
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D898- Other specified disorders involving the immune mechanism, not elsewhere classified Health Condition 2: null- Symptomatic Oral Lichen Planus patients coming to the OPD of Oral Medicine and Radiology Department of S.P.D.C. DMIMS Sawangi, Wardha and fulfilling the inclusion criteria.

Interventions

Intervention1: Neem leaves extract mouth wash: Neem leaves mouthwash (5-20%) will be given to symptomatic oral lichen planus patients (20 patients). They have to use it thrice daily and will be evalua

Sponsors

Dr Ashita Kalaskar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Symptomatic Patients with any clinical types and manifestations of OLP and those confirmed histopathologically will be included in the study. 2.Patients who have discontinued previous treatment for OLP for last six months.

Exclusion criteria

Exclusion criteria: 1.Patients younger than 16 years old. 2.Patients with skin lesions. 3.Patients with non symptomatic OLP lesions 4.Patients with lesions showing malignant or dysplasic changes. 5.Patients undergoing any other treatment for oral lichen planus. Pregnant and nursing woman. Patients having systemic problems or under any medications for the same. Patients having habit of chewing tobacco and betelnut or smoking.

Design outcomes

Primary

MeasureTime frame
Burning sensation will be evaluated by visual analog scale. The severity of lesions on each side will be evaluated by Thongprasom criteria.Timepoint: Burning sensation and The severity of lesions on each side will be evaluated on 1st day, 3rd day, 7th day, 2nd week, 3rd week, 4th week, 2nd month, 3rd month.

Secondary

MeasureTime frame
Acceptability of neem mouthwash. Total duration required to decrease the symptoms. Recurrence of the lesions in two months follow-up.Timepoint: 2nd and 3rd month folow-up

Countries

India

Contacts

Public ContactDr Ashita Kalaskar

Government Dental College and hospital, Nagpur

kalaskarashita@gmail.com8550928585

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026