Topical agents in arresting dental caries

Efficacy of 38% silver diamine fluoride (SDF) and 5% sodium fluoride (SF) in dental caries prevention- A double blinded parallel group multicenter randomised trial.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/08/015524

Enrollment

1000

Registered

2018-08-29

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Early Childhood Caries

Interventions

Intervention1: 38% silver diamine fluoride: Silver diamine fluoride is globally accepted treatment for topical application to arrest dental Caries in children Control Intervention1: 5% sodium fluoride

Eligibility

Inclusion criteria

Inclusion criteria: 1. Cooperative children with one or more smooth surface Caries. 2. Parents and children willing to participate. 3. Healthy children

Exclusion criteria

Exclusion criteria: 1. Parents not willing to participate. 2. Children with known allergy or any systemic illness.

Design outcomes

Primary

Measure	Time frame
Reduction in incidence of new carious lesionTimepoint: 3months, 6months and 1year	—

Secondary

Measure	Time frame
R suction in S mutans level in plaque and salivaTimepoint: 3months, 6months and 1year;Reduction in plaque index scoresTimepoint: 3months, 6months and 1year	—

Countries

India

Contacts

Public ContactMahesh

Saveetha Dental College & Hospital

maheshpedo@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026