Does pouring of local anaesthetics and adding dexmedetomidine in local anaesthetics drop by drop over incision wound prevent post surgical pain in patients who had lower spine surgery.

Post-Operative Analgesic Effect of Bupivacaine alone and with Dexmedetomidine in Wound Instillation for Lumbar Laminectomy: A Randomised Control Trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/08/015463

Enrollment

Registered

2018-08-24

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- patients of age group 18 to 60 yrs with ASA 1 or 2, planned for lumbar laminectomy under general anaesthesia.

Interventions

Intervention1: bupivacaine drug dexmedetomidine drug: bupivacaine is a local anaesthetic agent and dexmedetomidine is an alpha2 agonist which potentiates the effect of local anaesthetics. Control Inte

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA physical status I and II. 2. Age 18 to 60yrs of either sex, 3. Scheduled for lumbar laminectomy under general anaesthesia

Exclusion criteria

Exclusion criteria: 1.Patients with spinal stenosis, 2.Planned to have multiple level or double site laminectomy, 3.Patients who underwent prior lumbar disc surgery, 4.Have ASA III-IV status, 5.Prior neurological deficits, 6.Preoperative opioid use or any history of substance abuse or on steroids, 7.Have known local anaesthetics allergy, 8.Bleeding, cerebrospinal fluid leak, or requiring placement of a drain.

Design outcomes

Primary

Measure	Time frame
. post operative pain score. Duration of analgesia, total analgesic requirement and pain score in 24 hours will be recorded.Timepoint: 0 hr ,every 1 h till 8 hrs and then every 6 hrs till 24 hrs	—

Secondary

Measure	Time frame
vital parameters of patients. side effects if anyTimepoint: up to 24 hrs.	—

Countries

India

Contacts

Public ContactUrvashi Yadav

U.P.U.M.S, Saifai

drurvikgmu@gmail.com07500186161

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026