Health Condition 1: I958- Other hypotension
Conditions
Interventions
Intervention1: Fluid restriction and active fluid removal: 1. Ventilated pediatric patients will be enrolled
2. The positive balance accumulated will be measured by daily weight
3. Once hemodynamicall
Sponsors
Dr Kaushik Maulik
Dr Narayanan P
Eligibility
Inclusion criteria
Inclusion criteria: 1. All ventilated children between 2 completed months and 7 completed years admitted to PICU will be included 2. The included children must have received at least one fluid bolus 3. Must have achieved hemodynamic stability at enrolment defined by: MAP >5th centile CRT Not required any more fluid bolus or inotropes in last 12 hours
Exclusion criteria
Exclusion criteria: 1. Child with severe acute malnutrition (SAM) 2. Child with decompensated chronic liver disease and chronic kidney disease on RRT 3. Child with clinically suspected cardiogenic shock/myocarditis/acquired and congenital heart diseases in CCF 4. Children undergoing treatment for raised ICP with fluid restriction 5. Children with no evidence of fluid overload as assessed by body weight(defined as 10% increase from admission weight) 6. Children with severe anemia and hypoalbuminemia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the outcome of mechanically ventilated children undergoing fluid restriction and active fluid removal as compared to those with conventional fluid management in terms of daily Pediatric logistic organ dysfunction score (PELOD)Timepoint: This will be measured till 48 hours of sustaining nil balance or cessation of mechanical ventilation in the intervention group or till cessation of mechanical ventilation in the control group | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. ICU mortality 2. Duration of PICU stay 3. Ventilator free days 4. Requirement of RRTTimepoint: These will be measured till child is shifted out of PICU | — |
Countries
India
Contacts
Public ContactKAUSHIK MAULIK
Jawaharlal Institute of Postgraduate Medical Education and Research Puducherry
Outcome results
None listed