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Role of urea and ureolytic bacteria in dental calculus

Role of urea and ureolytic bacteria in dental calculus:-A clinical, biochemical and microbiological study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/08/015429
Enrollment
135
Registered
2018-08-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Not applicable: Not applicable

Sponsors

Liberia Libertina Dsouza
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Subjects having a minimum of 24 natural teeth excluding the third molars 2.Presence of dental calculus on the surfaces of the teeth 3.Subjects should be systemically healthy 4.No history of periodontal treatment in the last 6 months 5.Control subjects will be age and gender matched to test group subjects

Exclusion criteria

Exclusion criteria: 1.Patients with a history of any systemic disease (Diabetes mellitus, hypertension, liver disease, kidney disease ) 2.Patients with a history of antibiotic, anti- inflammatory or immunosuppressive drug therapy 6 month prior to the study. 3.Patients with history of any salivary gland diseases 4.Patients with any apparent oral infections (i.e. herpes or candidiasis ) 5.Patients with a history of radiation therapy. 6.Pregnant and lactating women. 7.Patients who are chronic smokers, tobacco users and alcohol users. 8.Denture wearers.

Design outcomes

Primary

MeasureTime frame
To measure levels of salivary urea, evaluate the presence and quantify the amount of ureolytic bacteria within dental calculus using gram staining, bacterial culture, biochemical reactions and to determine a possible correlation between salivary urea and ureolytic bacteria in dental calculus in patients with good, fair and poor oral hygiene.Timepoint: Within 24 hours

Secondary

MeasureTime frame
To evaluate the periodontal status using gingival index, clinical attachment loss , pocket probing depth and to determine a possible correlation between salivary urea and periodontal status in patients with good, fair and poor oral hygiene.Timepoint: Within 24 hours

Countries

India

Contacts

Public ContactLiberia Libertina Dsouza

Goa Dental College and Hospital

jamessamueldental@gmail.com9822151608

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026