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Effect of making the local anaesthetic drug (lignocaine) less acidic which is given for reducing the pain that occurs while injecting another drug (propofol) used for giving anaesthesia.

Effect of alkalization of preservative free lignocaine for pain due to propofol injection: A prospective, double blind study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/08/015418
Enrollment
150
Registered
2018-08-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- American Society of anaesthesiology physical status 1 and 2

Interventions

Intervention1: alkalized preservative free lignocaine: 5 ml of normal saline with 4 ml of preservative free lignocaine with 1 ml of 8.4 percent soda bicarbonate duration of therapy not applicable In

Sponsors

kasturba medical college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American society of anaesthesiology physical status 1 and 2

Exclusion criteria

Exclusion criteria: American society of anaesthesiology physical status 3 and 4, history of allergy to any of the study drugs

Design outcomes

Primary

MeasureTime frame
reduction of pain on propofol injection- McCrirrick and Hunter pain scoreTimepoint: 1 time point- post intervention—

Secondary

MeasureTime frame
NATimepoint: NA—

Countries

India

Contacts

Public ContactEeshwar MV

Kasturba Medical College, Manipal

kini.gurudas@gmail.com984569107

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026