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Comparing pain relieving efficacy of oral clonidine and oral pregabalin given pre-emptively to patients planned for upper limb surgeries under regional anesthesia

Comparative analgesic efficacy of pre-emptive oral clonidine and oral pregabalin in patients undergoing upper limb surgeries under supraclavicular block.A randomised,controlled prospective study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/08/015353
Enrollment
90
Registered
2018-08-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients posted for upper limb surgeries under supraclavicular block having ASA Grade I-II.

Interventions

Intervention1: Supraclavicular block: USG supraclavicular block will be given using 20ml of 2% lignocaine with adrenaline (1 in 2 lakhs) will be injected and sensory and motor effects will be noted. C

Sponsors

Dr RPGMC Kangra at Tanda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Scheduled for upper limb surgeries under supraclavicular block. 2. ASA Grade I-II. 3. BMI 18.5-29.9.

Exclusion criteria

Exclusion criteria: 1. Patientâ??s refusal for block 2. Patients with known drug allergy to study 3. Patients who have taken analgesics 48hrs before 4. Use of antiepileptics drugs 5. Hepatic and renal pathologies affecting drug clearence 6. History of long term usage of NSAIDs and opioid analgesics 7. Patient in whom the block effect will be partial and will require supplementary analgesic 8. Diabetes mellitus and other neuropathic disorders 9. Any contraindications for peripheral nerve blocks 10. Coagulopathy disorders 11. Psychiatric disorders 12. Addiction to any drug

Design outcomes

Primary

MeasureTime frame
To study and compare block characteristics and rescue analgesic requirement with pre-emptive oral clonidine and oral pregabalin.Timepoint: 24hours—

Secondary

MeasureTime frame
To study and compare post-operative sedation and patient satisfaction.Timepoint: 24hours—

Countries

India

Contacts

Public ContactSheena Sharma

Dr. R.P.G.M.C Kangra at Tanda.

drjaisingh62@gmail.com9418070893

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026