Skip to content

Comparing the effectiveness of terbinafine cream and ciclopirox cream alone and in combination in the treatment of ringworm (fungal infection)

Comparative efficacy of 1% terbinafine hydrochloride cream and 1% ciclopirox olamine cream alone and in combination in the treatment of dermatophytosis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/08/015305
Enrollment
60
Registered
2018-08-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B359- Dermatophytosis, unspecified

Interventions

Intervention1: GROUP 1 : 20 patients with topical 1% terbinafine hydrochloride cream twice daily for 6 weeks. Control Intervention1: GROUP 2: 20 patients with topical 1% ciclopirox olamine cream twice

Sponsors

Department of Dermatology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Koh positivity on direct microscopy showing septate hyphae of dermatophytosis 2. Body surface area less than 10%, not requiring systemic therapy 3. All age groups involved

Exclusion criteria

Exclusion criteria: 1. Patients with co-existing dermatophytosis involving hair, nail, palms and soles 2. Patients who have used any antifungal drugs or steroids in the last 4 weeks 3. Pregnant and lactating women

Design outcomes

Primary

MeasureTime frame
All the patients will be assessed for therapeutic results by clinical evaluation and KOH examination at 3, 6 and 9 weeks of initiation of therapy. Complete resolution of lesions except residual pigmentary changes shall be regarded as clinical cure and KOH negativity shall be regarded as mycological cure.Those achieving complete cure will be followed up at 9th week to look for any relapse.Timepoint: 3 weeks 6 weeks 9 weeks

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactDr Karan Chhabra

Goverment Medical College and Hospital, Chandigarh

malabhalla@yahoo.co.in9646121545

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026