Gum surgery with bone regenerative techniques

COMPARATIVE STUDY OF DEMINERALIZED FREEZE DRIED BONE ALLOGRAFT (DFDBA) ALONE AND WITH 1% METFORMIN IN THE TREATMENT OF INTRA BONY DEFECTS IN PATIENTS WITH CHRONIC PERIODONTITIS- IN VIVO STUDY.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/08/015285

Enrollment

Registered

2018-08-13

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Demineralized Freeze Dried Bone Allograft with 1% metformin gel: Demineralized Freeze Dried Bone Allograft with 1% metformin gel in treatment of intrabony defects Control Intervention1:

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with periodontal disease with a possible indication for flap surgery and having at least two intra bony defects, one on either side of the same arch, with interproximal probing depth (PD) of at least 5 mm or more after phase I therapy. 2. Patients maintaining proper oral hygiene status. 3. Systemically healthy patients. 4. Patients who give informed consent to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Pregnant and lactating females. 2. Patients consuming tobacco in any form. 3. Patients who have undergone periodontal surgical therapy in the last 6 months in the same site. 4. Patients with aggressive periodontitis.

Design outcomes

Primary

Measure	Time frame
There is a difference in results clinically and radiographically between demineralized freeze dried bone allograft alone and with 1% Metformin in the treatment of intra bony defects in the patients with chronic periodontitis.Timepoint: clinical evaluation at baseline, 3months, 6months, 9months. radiographic evaluation at baseline,9 months	—

Secondary

Measure	Time frame
There is a difference in results clinically and radiographically between demineralized freeze dried bone allograft alone and with 1% Metformin in the treatment of intra bony defects in the patients with chronic periodontitis.Timepoint: clinical evaluation at baseline, 3months, 6months, 9months. radiographic evaluation at baseline,9 months	—

Countries

India

Contacts

Public ContactDr Rutuja Donde

Terna Dental College and Hospital

drdipikamitra@gmail.com9820180406

Outcome results