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A study to compare the degree of postoperative pain relief and side effects of pregabalin versus tramadol when given preoperatively in breast cancer surgeries patients

A study to compare the postoperative analgesic effect of pregabalin and tramadol in breast cancer surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/08/015232
Enrollment
90
Registered
2018-08-08
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: C509- Malignant neoplasm of breast of unspecified site Health Condition 3: C509- Malignant neoplasm of breast of unspecified site

Interventions

Intervention1: Morphine 100mg intravenous infusion using PCA device for first 24 hours postoperatively: To compare the morphine sparing and analgesic effect of tramadol and pregabalin as premedicant i

Sponsors

Shri Guru Ram Das Institute of Medical Sciences and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade 1 and 2 patients undergoing breast cancer surgeries

Exclusion criteria

Exclusion criteria: 1.Age less than 18 and greater than 65 years 2.Patients refusal to take part in the study 3.Patients on any of the study drugs prior to the surgery. 4.Weight less than 40 kgs 5.Patients with known hypersensitivity to study drugs 6.Patients having history of drug abuse 7.Patients who are mentally retarded 8.ASA grade 3 and 4 6

Design outcomes

Primary

MeasureTime frame
Duration of postoperative analgesiaTimepoint: Duration of analgesia from drug administration to VAS equals to or more than 4 in postoperative period in first 24 hours—

Secondary

MeasureTime frame
1.Intraoperative haemodynamic stability 2.Sideffects of study drugs 3.Total dose of postoperative analgesic requirementsTimepoint: 1.Intraoperative haemodynamic stability upto end of surgery 2.In first 24 hours—

Countries

India

Contacts

Public ContactDr Chandna Badhan

Sri Guru Ram Das Institute Of Medical Sciences And Research

drruchisgrd@gmail.com9814320805

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026