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Correlation of Interleukin with viruses in gum disease.

Correlation of Interleukin 28A mRNA expression with herpes viruses in chronic and aggressive periodontitis patients: A polymerase chain reaction study.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/08/015221
Enrollment
90
Registered
2018-08-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Chronic and Aggressive patients

Interventions

None listed

Sponsors

DR SHIVAPRASAD BM
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Systematically healthy patients and showing the absence of clinical manifestations of periodontal disease. 2 Chronic periodontitis patients having at least 20 natural teeth and minimum of 6 teeth with periodontal pockets >= 5mm and clinical attachment level >= 3-4mm. 3 All the patients should be systematically healthy and should not have received periodontal treatment for last 6 months prior to the clinical examination and sampling. 4 Generalised aggressive periodontitis patients with clinical attachment level >= 5mm affecting atleast 3 teeth other than first molars and incisors and moderate to severe bone loss as assessed by radiographs

Exclusion criteria

Exclusion criteria: 1 Smokers 2 Systemic diseases like diabetes mellitus, heart diseases, rheumatoid arthritis, hepatitis and other systemic diseases that can alter the course of periodontal disease. 3 Diseases of oral hard and soft tissue except caries and periodontitis. 4 Subjects on any medication taken within last 6 months which may alter the periodontal status. 5 Pregnant and lactating mothers.

Design outcomes

Primary

MeasureTime frame
Levels of Interleukin 28A mRNA expression in gingival crevicular fluid and gingival tissues of chronic and aggressive periodontitis patientsTimepoint: Levels of Interleukin 28A mRNA expression in gingival crevicular fluid and gingival tissues of chronic and aggressive periodontitis patients will be assessed at baseline immediately after collection of samples—

Secondary

MeasureTime frame
Gingival index score clinical attachment level and probing pocket depth of chronic and aggressive periodontitis patientsTimepoint: Gingival index score clinical attachment level and probing pocket depth of chronic and aggressive periodontitis patients will be assessed at baseline at the time of sample collection—

Countries

India

Contacts

Public ContactDRSHIVAPRASAD BM

RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES

drpaunamipaulperio@gmail.com9740748347

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026