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Comparison of two doses of ketamine along with steroid and local anaesthetic agent for relief of low backpain

To compare the analgesic efficacy of 25 mg and 50 mg Ketamine as an adjunct to Trimacinolone and Bupivacaine in patients of chronic low backache

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/08/015209
Enrollment
90
Registered
2018-08-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M999- Biomechanical lesion, unspecified Health Condition 2: M997- Connective tissue and disc stenosis of intervertebral foramina Health Condition 3: null- patients suffering from low backache Health Condition 4: M498- Spondylopathy in diseases classified elsewhere

Interventions

Intervention1: Lumbar epidural steroid injection: Ketamine 25 mg v/s ketamine 50 mg v/ s placebo given through lumbar epidural Intervention2: Dr Ruchi Gupta: Ketamine 50 mg and 25 mg Triamcinolone 40

Sponsors

Sri Guru Ram Das Institute Of Medical Sciences And Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: history of low backache with or without radiculitis of minimum 3 months duration and no relief with conservative treatment

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
To evaluate the analgesic efficacy of adding different doses (25 mg vs 50 mg) of ketamine to bupivacaine and triamcinolone as compared to saline triamcinolone and bupivacaine. The analgesic efficacy will be assessed in terms of duration of pain free intervals after first block and in number of repeat blocks.Timepoint: 2 years—

Secondary

MeasureTime frame
Effect of ventral spread of drug solutions on VAS(Visual Analogue Score).Timepoint: 2 years;To compare the effect of 25 mg and 50 mg of epidural ketamine compared to placebo on a) VAS b) Quality of life scores including Roland Morris disability questionnaire and Revised Oswestry LBP disability c) Depression score d) Patient satisfaction score.Timepoint: 2 years;To study procedural complications and side effects of study drugs will be noted.Timepoint: 2 years—

Countries

India

Contacts

Public ContactDr Harmandeep Kaur

Sri Guru Ramdas Institute of Medical Sciences and Research

drlakshmimahajan@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026