Health Condition 1: null- Grade-I Hypertensive patients
Conditions
Interventions
Intervention1: Cilnidipine: 10mg
oral tablet once daily in morning for 52 weeks
Control Intervention1: Amlodipine: 5mg oral tablet
once daily in morning
for 52 weeks
Sponsors
NRS Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 1 Newly diagnosed case of gradeI hypertension 2 Adult age group from 18 yrs to 80 yrs 3 Patients willing to give written consent 4 Hypertensive patients without other co morbid factors like angina cardiac ischemia cerebrovascular disease peripheral vascular disease cardiac infarction renal disease preexisting edema corpulmonale anaemia hypoproteinemia nephrotic syndrome hepatic cirrhosis
Exclusion criteria
Exclusion criteria: 1 Patients taking NSAIDS and Amantadine 2 Patients taking other anti hypertensive drugs 3 Pregnancy 4 Patients taking antipsychotic drugs 5 Patients taking drugs that cause Pedal Edema 6 Patients not responding in treatment during 2 weeks 7 Patients taking less than 30 percent of the tablets dispensed as study medication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1 Changes Of systolic Blood Pressure From baseline to normal 2 Changes Of Diastolic Blood Pressure From Baseline to normalTimepoint: 52 weeks after starting of treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| 1 Heart rate changes 2 Changes in ecg 3 Changes in estimated glomerular filtration rate 4 Changes in albumin creatinine ratio 5 Changes in echocardiography Timepoint: 52 weeks after starting of treatment | — |
Countries
India
Contacts
Public ContactDr Priyatosh Saha
NRS MEDICAL COLLEGE
Outcome results
None listed