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Relationship of herpes virus with interleukin in gum diseases

Relationship between mRNA expression of interleukin 29 and herpes viruses in chronic and aggressive periodontitis patients:A polymerase chain reaction study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/07/015141
Enrollment
90
Registered
2018-07-31
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Chronic and aggressive periodontitis patients

Interventions

None listed

Sponsors

Dr Shivaprasad BM
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Systematically healthy patients and showing the absence of clinical manifestations of periodontal disease. 2.Chronic periodontitis patients having at least 20 natural teeth and minimum of 6 teeth with periodontal pockets >= 5mm and clinical attachment level >= 3-4mm. 3.All the patients should be systematically healthy and should not have received periodontal treatment for last 6 months prior to the clinical examination and sampling. 4.Generalised aggressive periodontitis patients with clinical attachment level >= 5mm affecting atleast 3 teeth other than first molars and incisors and moderate to severe bone loss as assessed by radiographs

Exclusion criteria

Exclusion criteria: 1.Smokers 2.Systemic diseases like diabetes mellitus, heart diseases, rheumatoid arthritis, hepatitis and other systemic diseases that can alter the course of periodontal disease. 3.Diseases of oral hard and soft tissue except caries and periodontitis. 4.Subjects on any medication taken within last 6 months which may alter the periodontal status. 5.Pregnant and lactating mothers.

Design outcomes

Primary

MeasureTime frame
Levels of Interleukin 29 mRNA expression in GCF and gingival tissue of chronic and aggressive periodontitis patientsTimepoint: Collection of GCF and gingival tissue at baseline

Secondary

MeasureTime frame
Gingival index Clinical attachment level Probing pocket depthTimepoint: At baseline

Countries

India

Contacts

Public ContactDR SHIVAPRASAD BM

RAJARAJESWARI DENTAL COLLEGE AND HOSPITAL BANGALORE

umesameeraperio@gmail.com8147800182

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026