â??Clinical trial of Siddha drugs Parangipattai Kudineer (Internally) and Sivappu Thylam (Externally) in the treatment of Kalanjaga Padai (Psoriasis) with and without Yogam therapyâ??

â??Preclinical and comparative clinical trial of Siddha drugs Parangipattai Kudineer (Internally) and Sivappu Thylam (Externally) in the treatment of Kalanjagapadai (Psoriasis) with and without Yogam therapy (Agathavam Ettu)â??

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/07/015115

Enrollment

Registered

2018-07-30

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients with symptoms of dry erythematous macules with silvery scales without any structural changes in any part of the body Health Condition 2: L409- Psoriasis, unspecified Health Condition 3: L409- Psoriasis, unspecified

Interventions

Intervention1: Parangipattai Kudineer (Internally) and Sivappu Thylam (Externally): Parangipattai Kudineer is a polyherbal formulation in a dosage of 30ml internally,Three times a day and Sivappu Thy

Eligibility

Inclusion criteria

Inclusion criteria: 1)History of Non Insulin Dependent Diabetes Mellitus 2)Dry erythematous macules with silvery scaly lesion without any structural changes in any part of the body. 3) Itching 4)Erythema 5)Scaling 6)Auspitz sign + 7)Candle crease sign + 8)Willing to give specimen of blood for the investigation whenever required. 9)Willing to take photograph 10)Willing to participate in trial and signing consent by fulfilling the condition of Proforma.

Exclusion criteria

Exclusion criteria: 1.History of Insulin Dependent Diabetes Mellitus 2.Pregnancy and lactation 3.History of Psoriasis with evidence of any other skin disease or Evidences of secondary infection in the lesions. 4.History of Psoriatic arthropathy 5.History of Cardiac diseases 6.History of Hansenâ??s disease 7.History of any other chronic illness

Design outcomes

Primary

Measure	Time frame
Efficacy of the trial drug measured by PASI Score. Timepoint: 1-48 DAYS	—

Secondary

Measure	Time frame
1.To study the Siddha diagnostic methods such as Envagai thervu and Manikkadai Nool as complementary measures for diagnosis in Kalanjaga padai patients. 2.To carry out the biochemical analysis of trail medicine Parangipattai kudineer (Internally) 3.To evaluate the toxicity study of trail medicine Parangipattai kudineer (Internally) Timepoint: 1-48 DAYS	—

Countries

India

Contacts

Public ContactDr M V Mahadevan

Ayothidass pandithar hospital, National Institute of Siddha

njmuthu@hotmail.com9444206843

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026