Comparasion of oral melatonin and clonidine for attenuation of increase BP and Pulse rate due to tube placement in trachea for anaesthesia posted for surgery.

Comparative evaluation of oral melatonin and clonidine for attenuation of haemodynamic response to tracheal intubation-A Prospective Randomized Double Blind Comparative Study.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/07/015112

Enrollment

Registered

2018-07-30

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA grade I posted for elective surgery Health Condition 2: K87- Disorders of gallbladder, biliarytract and pancreas in diseases classified elsewhere

Interventions

Control Intervention1: Tab melatonin 6 mg: 120 min before induction of anaesthesia Control Intervention2: tab clonidine 200 microgm: 120 min before induction of anaesthesia

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade I and II Scheduled for elective surgery

Exclusion criteria

Exclusion criteria: Patient with previous treatment with study drug Difficult intubation

Design outcomes

Primary

Measure	Time frame
To assess and compare the effects of oral melatonin and oral clonidine on haemodynamics.Timepoint: At the time of induction, laryngoscopy ,tracheal intubation then at 0, 1, 3, 5 and 10 min after intubation.	—

Secondary

Measure	Time frame
Observation of any side effectsTimepoint: 24 hours postoperatively	—

Countries

India

Contacts

Public ContactDr Lalaram Choudhary

MBGH

drsanchoudhary@gmail.com9462102856

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026