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Reducing craving in alcohol dependence using electrical stimulation of brain

Behavioral effects of transcranial direct current stimulation (tDCS) induced dorsolateral prefrontal cortex plasticity in alcohol dependence

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/07/015101
Enrollment
20
Registered
2018-07-27
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Alcohol dependent individuals

Interventions

Intervention1: transcranial direct current stimulation (tDCS): 10 subjects will be given active tDCS of 2mA for 20 minutes twice daily for consecutive 10 days. The anode will be positioned over the le

Sponsors

All India Institute of Medical Sciences New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age 18-50 years 2. Males 3. Willing to give informed consent 4. Fulfilling criteria of alcohol dependence as per International Classification of Diseases version 10 (ICD-10)

Exclusion criteria

Exclusion criteria: 1. Patients with chronic unstable neurological or other physical illness 2. Suffering from any other substance dependence (except caffeine or nicotine), as assessed by Mini International Neuropsychiatric Interview (MINI) screen 3. History of significant head trauma 4. Having implanted device or metals in brain/head or cardiac pacemaker

Design outcomes

Primary

MeasureTime frame
Changes in scores of Visual Analogue Scale (VAS) for CravingTimepoint: At baseline before first session, after fifth session, last session and one month after last session

Secondary

MeasureTime frame
Changes in Montreal Cognitive Assessment (MoCA) scoresTimepoint: At baseline before first session, after fifth session, last session and one month after last session;Changes in scores of Hamilton Depression Rating Scale (HDRS)Timepoint: At baseline before first session, after fifth session, last session and one month after last session;Side effect checklist for tDCSTimepoint: At baseline before first session, after fifth session, last session and one month after last session

Countries

India

Contacts

Public ContactRohit Verma

All India Institute of Medical Sciences

rohit.aiims@gmail.com9868005491

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026