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A study to compare the rates of decreased calcium levels in blood after total thyroid removal operation when using Indocyanine green dye v/s no dye usage

Incidence of postoperative hypocalcemia after Indocyanine Green fluorescence guided v/s Conventional assessment of parathyroid function following total thyroidectomy - A Randomised Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/07/015095
Enrollment
20
Registered
2018-07-27
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- All Patients undergoing total thyroidectomy for both benign and malignant conditions Health Condition 2: E012- Iodine-deficiency related (endemic) goiter, unspecified Health Condition 3: E010- Iodine-deficiency related diffuse(endemic) goiter Health Condition 4: E011- Iodine-deficiency related multinodular (endemic) goiter Health Condition 5: E011- Iodine-deficiency related multinodular (endemic) goiter Health Condition 6: C73- Malignant neoplasm of thyroid gland Health

Interventions

Intervention1: Indocyanine Green dye injection: After total thyroidectomy, Indocyanine Green dye will be mixed with 5 ml sterile water and 2.5 ml will be injected intravenously. The injection could b

Sponsors

All India Institute of Medical Sciences New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All Patients undergoing total thyroidectomy for both benign and malignant conditions

Exclusion criteria

Exclusion criteria: 1. Patients with known renal impairment or iodine allergy 2. Patients with concomitant hyperparathyroidism 3. Age 70 years 4. Pregnancy 5. Patients undergoing central compartment neck dissection or modified radical neck dissection

Design outcomes

Primary

MeasureTime frame
1. To evaluate the use of ICG angiography to assess parathyroid gland function after thyroid surgery and thereby, take appropriate steps to prevent postoperative hypocalcemia 2. To compare the incidence of postoperative hypocalcemia after ICG guided assessment of parathyroid function with that of conventional methodsTimepoint: Postoperative Day 0 and postoperative day 1—

Secondary

MeasureTime frame
To find the correlation between parathyroid fluorescence after ICG dye injection and POD0 and POD1 calcium levels and POD1 PTH levelsTimepoint: Postoperative day 0 and postoperative day 1—

Countries

India

Contacts

Public ContactKeshav Agarwal

All India Institute of Medical Sciences, New Delhi

varnaseenu@hotmail.com9910834455

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026