FindTrial
Sign In

comparison between the effect of two medicines used in psoriasis in different doses and combination.

Comparative study of efficacy of combination of half dose of methotrexate and cyclosporine vs full dose of methotrexate alone in Chronic Plaque Psoriasis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/07/015044
Enrollment
140
Registered
2018-07-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- chronic plaque psoriasis

Interventions

Intervention1: methotrexate and cyclosporine: comparative study of full dose - 0.3 mg/kg/week of methotrexate with a combination of half dose (0.15mg/kg/week) of methotrexate and cyclosporine (2.5 mg/

Sponsors

IMS BHU
Lead Sponsor
Satyendra Kumar Singh
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients with chronic plaque psoriasis with BSA > 10, PASI >10

Exclusion criteria

Exclusion criteria: Pregnancy,lactation, child bearing age group in females, alcoholic, liver disorders, kidney disorders, Hemoglobin < 8 g/dl, TLC < 400O per microlitre, platelet <1 lakh per microlitre, immunosupression,

Design outcomes

Primary

MeasureTime frame
Achievement of PASI 75Timepoint: Followed every 2 weeks for 12 weeks—

Secondary

MeasureTime frame
Experience as of primary outcomeTimepoint: Followed every 2 weeks for 12 weeks—

Countries

India

Contacts

Public ContactSatyendra Kumar Singh

Institute of Medical Sciences

drsatyendraderma@gmail.com9198120582

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026