Study of effectiveness of Granisetron for prevention of fall in blood pressure following anesthesia in pregnant patients undergoing surgery

"Study of effectiveness of Intravenous Granisetron in prevention of hypotension following spinal anesthesia in parturients posted for elective cesarean section" - A Prospective, Randomized, Double blind study

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/07/015038

Enrollment

200

Registered

2018-07-24

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- All pregnant patients who need cesarean section surgery

Interventions

Intervention1: INTRAVENOUS GRANISETRON: Dose - 1mg Granisetron Frequency - Single dose Route - Intravenous Total Duration of therapy - Not applicable as the study drug will only be given once. Contro

Eligibility

Inclusion criteria

Inclusion criteria: Healthy term parturients posted for elective LSCS under Spinal anesthesia

Exclusion criteria

Exclusion criteria: Patient refusal, Contraindications to Spinal anesthesia, Allergy to study drug, Patients on serotonin agonists or antagonists, Presence of other co-existing systemic diseases, Emergency surgeries

Design outcomes

Primary

Measure	Time frame
Effectiveness of 1mg IV Granisetron in preventing hypotension following Spinal anesthesiaTimepoint: One hour after completion of surgery	—

Secondary

Measure	Time frame
To observe any other significant adverse events secondary to Granisetron administrationTimepoint: 24 hours after completion of surgery	—

Countries

India

Contacts

Public ContactBhanu Teja Gudiwada

TATA MAIN HOSPITAL

dr.abhishekchatterjee@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026