Health Condition 1: null- Having neurological symptoms at hospital admission suspicious for acute stroke
Conditions
Interventions
None listed
Sponsors
Christian Medical College
Johann Wolfgang Goethe University
Eligibility
Inclusion criteria
Inclusion criteria: 1. Presence of neurological symptoms at hospital admission suspicious for acute stroke 2. Time interval from symptom onset to study inclusion
Exclusion criteria
Exclusion criteria: 1. Ischemic stroke, intracerebral hemorrhage or transient ischemic attack within the last three months 2. Patients participating in other stroke trials/research 3. Known history of brain tumor at any time in patient history 4. Evidence for traumatic brain injury with the last 3 months 5. Participant in another stroke study 6. Informed consent not given
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Diagnostic accuracy (sensitivity, specificity, positive predictive value, negative predictive value) of GFAP for differentiating patients with ICH from patients with ischemic stroke (including TIA) and stroke mimics. 2. Gold standard is the diagnosis of ICH, ischemic stroke (including TIA), or stroke mimic as determined at the end of hospital stay based on all available information. Timepoint: 1 month after the end of recruitment phase | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Analysis stratified for patients with a moderate to severe neurological deficit (NIHSS 9). 2. Analysis stratified for patients with different time windows (2 h, 2 to 6 h, 6 to 12 h) from symptom onset to blood withdrawal. 3. Correlation between GFAP values and ICH volume and location. Timepoint: At the time of result analysis | — |
Countries
India
Contacts
Public ContactDr Jeyaraj Durai Pandian
Christian Medical College
Outcome results
None listed