Effect of probiotic supplementation on feed tolerance and weight gain in low birth weight infants on tube feeds

Probiotic supplementation and its effect on feed tolerance and weight gain in low birth weight infants on orogastric feeds- A Randomized controlled trial

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/07/014991

Enrollment

Registered

2018-07-20

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Low birth infants on orogastric feeds

Interventions

Intervention1: Probiotic: Probiotic containing lactibacillus acidophilus, lactibacillus rhamnosus, bifidobacterium longum, saccharomyces boulardi in form of powdered sachet of 1g each Dose is 1.25Ã?10

Eligibility

Inclusion criteria

Inclusion criteria: All neonates with a birth weight between 1000 to 1800gm admitted to the NICU in whom enteral feeds can be started.

Exclusion criteria

Exclusion criteria: Neonates with weight Neonates with gastrointestinal anomalies. Neonates with major congenital malformations. Neonates in whom the feed could not be started by day 14 of life.

Design outcomes

Primary

Measure	Time frame
To compare the time taken(in days) to reach full enteral feeds(150ml/kg/day) in low birth weight infants on orogastric feeds between the probiotic and no probiotic group. To compare episodes of feed intolerance and weight gain in both the groups.Timepoint: Time taken to reach full enteral feeds	—

Secondary

Measure	Time frame
To compare the duration of hospital stay, incidence of NEC stage 2 or more, other morbidity and mortality during hospital stay in both the groups. Timepoint: Duration of hospital stay	—

Countries

India

Contacts

Public ContactDr Amarpreet kaur

GGS medical college and hospital faridkot

dr.amarpreet12@gmail.com9914030677

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026