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Blood gas assisted management of patients in major operations

DCO2 (Central venous to arterial CO2 difference) assisted goal directed hemodynamic management during major surgery, a randomized controlled trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/07/014987
Enrollment
80
Registered
2018-07-20
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- All adult patients scheduled for major surgeries

Interventions

Intervention1: CO2 GAP: In these patients. goal directed fluid therapy will be carried out as per a prespecified algorithm, based on SCVo2 and dCO2 Control Intervention1: Control Group: In these patie

Sponsors

AIIMS BHubaneswar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All adult ASA i-ii patients undergoing major surgeries and consenting for tjhe same will be included

Exclusion criteria

Exclusion criteria: Non consenting, severe uncontrolled comorbidity of any kind.

Design outcomes

Primary

MeasureTime frame
Organ FailureTimepoint: in ICU, at hospital discharge and 30 days after discharge—

Secondary

MeasureTime frame
To compare the difference between conventional and Goal directed therapies on the post-operative length of mechanical ventilation, ICU , hospital stay, QOL and and 30 day mortality in patients undergoing major surgeries. To compare the SCvO2, DCO2 levels separately in relation to primary outcomes. To compare PCvCO2-PaCO2/PaO2-PCvO2 in both groups and its relationship with primary outcome. Timepoint: 30 days after surgery—

Countries

India

Contacts

Public ContactDr Lohith Kumar

All India Institute of Medical Sciences

tripathyswagata@gmail.com8763400534

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026