Health Condition 1: O746- Other complications of spinal andepidural anesthesia during labor and delivery Health Condition 2: null- PREGNANT PATIENTS AT TERM GESTATION
Conditions
Interventions
Intervention1: Norepinephrine: Potent alpha adrenergic receptor agonist and relatively weak beta adrenergic receptors agonist.It is given as continuous fixed rate intravenous infusion at the rate of
Sponsors
Kovai Medical Center and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA I and II, 2. Singleton gestation >36 weeks, 3. Scheduled elective cesarean delivery under spinal anesthesia, 4. Fasting >6 h
Exclusion criteria
Exclusion criteria: 1. Pregnancy-related hypertensive disease, 2. Multiple gestation, 3. Gestational diabetes requiring insulin, 4. Documented history of postoperative nausea and vomiting, 5. Body mass index (BMI) >40 kg/m2, 6. Emergency caesarean section for maternal and/or fetal distress, 7. ASA III and IV patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To maintain maternal systolic and diastolic blood pressure in term parturients during spinal anaesthesia.Timepoint: The study infusion medication is started at the same time cerebrospinal fluid was obtained, immediately before injection of spinal medications. Blood pressure measured every minute from the start of study medication infusion till the baby delivery. | — |
Secondary
| Measure | Time frame |
|---|---|
| Nausea and vomitingTimepoint: intraoperative time;Apgar scoreTimepoint: at 1st and 5th minute of life;fetal heart rateTimepoint: at 5th minute of life;Maternal heart rateTimepoint: Every minute, from the time of start of infusion medication till the baby delivery.;perfusion indexTimepoint: every minute,from start of study medication infusion till the time of baby delivery;rescue boluses usedTimepoint: When blood pressure and heart rate falls below 20 percent of baseline values.;umblical cord blood analysisTimepoint: cord blood sample will be withdrawn just before delayed cord clamping. | — |
Countries
India
Contacts
Public ContactSilky Dhamija
KOVAI MEDICAL CENTER AND HOSPITAL
Outcome results
None listed