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TO STUDY THE EFFECTS OF GIVING HIGHER AMOUNT OF OXYGEN ON NAUSEA AND VOMITING AFTER SURGERY IN CHILDREN WHO ARE UNDERGOING SURGERY.

Effect of high inspired oxygen concentration on postoperative nausea and vomiting(PONV) in pediatric patients undergoing surgery. - "HOPES"TRIAL "H"igh "O"xygen in "PE"diatric "S"urgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/07/014974
Enrollment
140
Registered
2018-07-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- PEDIATRIC PATIENTS SCHEDULED FOR ELECTIVE SURGERY.

Interventions

Intervention1: HIGH FIO2/LOW FIO2: 80% OXYGEN/30% OXYGEN Intervention2: LOW FIO2: 30% OXYGEN Intervention3: CONTROL GROUP: LOW FIO2 GROUP PATIENTS WILL RECEIVE 30% OXYGEN INTRAOPERATIVELY. Control Int

Sponsors

INSTITUTE RESEARCH GRANT
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: PEDIATRIC PATIENTS UNDERGOING SURGERY OF EXPECTED DURATION MORE THAN 1 HOUR AND LESS THAN 4 HOUR.

Exclusion criteria

Exclusion criteria: EMERGENCY SURGERY,PATIENT ALREADY RECEIVING OXYGEN OR ON VENTILATOR,PATIENT REQUIRING POST-OP MECHANICAL VENTILATION,SEPSIS,BOWEL OBSTRUCTION,POOR NUTRITIONAL STATUS,ANEMIA (HB <8 GM%).

Design outcomes

Primary

MeasureTime frame
1.POST OPERATIVE NAUSEA AND VOMITING(24HR)Timepoint: 1.POST OPERATIVE NAUSEA AND VOMITING(24HR)—

Secondary

MeasureTime frame
2. SURGICAL SITE INFECTION 3.INFLAMMATORY MARKERS TNF ALPHA,SERUM SEROTONIN LEVELS 4.ADVERSE RESPIRATORY OUTCOMESTimepoint: 2.TILL TIME OF DISCHARGE FROM HOSPITAL 3.AT START OF SURGERY AND AT END OF SURGERY 4.TILL TIME OF DISCHARGE FROM HOSPITAL.—

Countries

India

Contacts

Public ContactBIKRAM KISHORE BEHERA

AIIMS,BHUBANESWAR

bikrambehera007@gmail.com9438884047

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 14, 2026