Health Condition 1: null- chronic cervical myelopathy Health Condition 2: M471- Other spondylosis with myelopathy
Conditions
Interventions
Intervention1: Intravenous fluid - Ringer lactate: Intravenous fluid pre-loading with 20 ml/kg of Ringer lactate over 30 minutes prior to induction of anaesthesia, followed by 2ml/kg/h maintenance
Con
Sponsors
Anto Paul
Eligibility
Inclusion criteria
Inclusion criteria: 1. Evidence of cervical myelopathy clinically or on imaging studies for more than three months and posted for surgery 2. American Society of Anaesthesiologists Class 1 - 2
Exclusion criteria
Exclusion criteria: 1. AtlantoAxial Dislocation and Cervico-Medullary Junction lesion 2. Tumour pathology 3. Pre-existing systemic disease on treatment - Diabetes Mellitus, COPD, Hypertension, Ischemic heart disease, Cardiac dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hypotension after induction of general anaesthesia for surgery in patients with chronic cervical myelopathyTimepoint: Pre-intervention, Post-intervention, 1 minute after induction, 3 minutes after induction, 5 minutes after induction, 1 minute after intubation, 3 minutes after intubation, 5 minutes after intubation, 5 minutes after positioning for surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Effect of autonomic dysfunction on post induction hypotension and autonomic function changes during and following induction using the ANS index.Timepoint: Pre-intervention, Post-intervention, 1 minute after induction, 3 minutes after induction, 5 minutes after induction, 1 minute after intubation, 3 minutes after intubation, 5 minutes after intubation, 5 minutes after positioning for surgery;Effect of hypotension on cerebral oxygen saturation (cSO2).Timepoint: Pre-intervention, Post-intervention, 1 minute after induction, 3 minutes after induction, 5 minutes after induction, 1 minute after intubation, 3 minutes after intubation, 5 minutes after intubation, 5 minutes after positioning for surgery;Hemodynamic parameters following induction in patients with chronic cervical myelopathyTimepoint: Pre-intervention, Post-intervention, 1 minute after induction, 3 minutes after induction, 5 minutes after induction, 1 minute after intubation, 3 minutes after intubation, 5 minutes after intubation, 5 minutes after positioning for surgery. | — |
Countries
India
Contacts
Public ContactDr Sriganesh K
National Institute of Mental Health and Neurosciences
Outcome results
None listed