Health Condition 1: null- Prostate cancer
Conditions
Interventions
Intervention1: INTENSITY MODULATED RADIOTHERAPY (IMRT) FOLLOWED BY STEREOTACTIC BODY RADIOTHERAPY (SBRT) BOOST: single arm of 15 patients of localised carcinoma prostate are treated with radiotherapy
Sponsors
Department of radiotherapy
Eligibility
Inclusion criteria
Inclusion criteria: 1.Previously untreated biopsy proven prostate adenocarcinoma. 2. Localized carcinoma prostate (Stage T1 T2 T3) as per TNM staging system. 3. Karnofsky performance scale (KPS) > 70 4. Normal Hemogram, renal and liver function. 5. Informed consent for participation in the study
Exclusion criteria
Exclusion criteria: 1. Carcinoma prostate other than adenocarcinoma histology. 2. Stage T4 3. Lymph nodal involvement N+ 4. Evidence of distant metastasis on chest X â?? ray or Bone Scan. 5. Patients having any uncontrolled co-morbid conditions. 6. Prior pelvic radiotherapy 7. Presence of 2nd malignancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To assess the acute toxicity occurring with treatment with IMRT followed by SBRT boost in localized prostate cancerTimepoint: Toxicities are assessed -- a)weekly during radiotherapy treatment b)at the end of first,second and third months of radiotherapy completion | — |
Secondary
| Measure | Time frame |
|---|---|
| 2. To evaluate the improvement or decline in urinary function with treatment. 3. To study the short-term treatment outcome on radiological basis. Timepoint: urinary function assesed weekly during treatment and 1st and 3rd month post treatment treatment response assessed post 3 months of treatment | — |
Countries
India
Contacts
Public ContactDrNarendra kumar
PGIMER
Outcome results
None listed