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Use of ondansetron to maintain blood pressure and heart rate under spinal anaesthesia

Evaluation of the effect of ondansetron on haemodynamics under spinal anaesthesia.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/07/014940
Enrollment
200
Registered
2018-07-18
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASAI and II patients posted for surgery under spinal anaesthesia

Interventions

Control Intervention1: Injection ondansetron intravenous: 0.1mg/kg diluted with normal saline to make total volume of 10ml

Sponsors

Dr kirandeep kaur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASAIand II patients posted for surgery to be done under spinal anaesthesia those who are willing to consent

Exclusion criteria

Exclusion criteria: ASAIII IV, contraindications to spinal anaesthesia, contraindications to ondansetron, parturients, chronic alcoholic, uncontrolled hypertension, morbidly obese, allergic to local anaesthetic used in the study

Design outcomes

Primary

MeasureTime frame
Vitals including MAP, HR, SPO2 will recorded at 2 minutes interval upto 20 minutes and then every 5 minutes interval till completion of the surgery. Patient will be shifted to post anaesthesia care unit and will be monitored 2 hourly interval to a total of 12 hours.Timepoint: Vitals including MAP, HR, SPO2 will recorded at 2 minutes interval upto 20 minutes and then every 5 minutes interval till completion of the surgery. Patient will be shifted to post anaesthesia care unit and will be monitored 2 hourly interval to a total of 12 hours.

Secondary

MeasureTime frame
Complications if any and total dose of atropine and ephedrine used to treat bradycardia and hypotension respectivelyTimepoint: At the end of the study

Countries

India

Contacts

Public ContactDr kirandeep kaur

Maharishi Markandeshwar Medical College and Hospital Kumarhatti

dr.kirandeep.kaur@mmusolan.org7986886099

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026