Health Condition 1: null- INFERTILE WOMEN WITH NO OTHER MEDICAL CO-MORBIDITY
Conditions
Interventions
Intervention1: tab sildenafil: 50 mg daily per orally from day 2 of menstrual cycle till day of ovulation trigger
Control Intervention1: granulocyte- colony stimulating factor: 2 mg intra-uterine inst
Sponsors
Department of Obstetrics Gynaecology AIIMS Patna
Eligibility
Inclusion criteria
Inclusion criteria: : infertile females attending gynaecology OPD,where other causes of infertility had been ruled out ( including male factor infertility, tubal factor, decreased ovarian reserve and tuberculosis) and patients with unexplained infertility with thin endometrium undergoing ovulation induction, who in previous cycle had already received estrogen supplementation and not benifitted much, will be enrolled for the study after taking informed consent
Exclusion criteria
Exclusion criteria: 1. Pt with husband factor, tubal factor or with poor ovrian reserve 2. Known hypersensitivity to the drug 3. Pts on any anti-anginal or antihypertensive drugs 4. Pts. With known liver disorders 5. Pts. With known kidney disorders - Pts. With heart disease
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| 1. Endometrial pattern( trilaminar) 2. chemical pregnancy rate 3. pregnancy rate 4. delivery rate Timepoint: day 20 after inj HCG | — |
Primary
| Measure | Time frame |
|---|---|
| endometrial thickness on the day of triggerTimepoint: on day of inj HCG | — |
Countries
India
Contacts
Public ContactMukta Agarwal
AIIMS, Patna
Outcome results
None listed