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COMPARISON BETWEEN TWO DRUGS TO CHECK THE EFFECTIVENESS ON HEMODYNAMIC PARAMETERS

A PROSPECTIVE RANDOMIZED COMPARATIVE STUDY OF INTRAVENOUS DEXEMEDETOMIDINE VERSUS MAGNESIUM SULPHATE [MgSO4] AS AN ADJUNCT DURING ANAESTHESIA FOR LAPROSCOPIC CHOLECYSTECTOMY

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/07/014901
Enrollment
70
Registered
2018-07-17
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ATTENUATION DURING ANESTHESIA IN LAPROSCOPIC CHOLECYSTECTOMY

Interventions

Intervention1: Inj magnesium sulphate: Inj magnesium sulphate 40mg/kg over 15 min in 20 ml NS intravenously Control Intervention1: INJ DEXMEDETOMIDINE : Inj Dexmedetomidine 1mcg/kg over 15 min in 20 m

Sponsors

SSG HOSPITAL VADODARA
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Age Group 18 -65years 2 ASA status I & II 3 Male / female Patients posted for laparoscopic cholecystectomy

Exclusion criteria

Exclusion criteria: • Anticipated difficult airway and obesity • Patient having allergy to study drug • Patient with systemic diseases like severe hypertension, cardiovascular, respiratory, neurological, psychological, hepatic, renal disease (diagnosed by clinical judgments and investigations) and on medication of above mentioned diseases • Patients with heart rate • Pregnant or lactating females • Patients who refuse to give consent

Design outcomes

Primary

MeasureTime frame
It will be expected that both drugs will be effectively able to attenuate hemodynamic stress response during anaesthesia for laparoscopic cholecystectomy with CO2 pneumoperitoneumTimepoint: 1. Baseline 2. Before and after infusion 3. Before and after intubation 4. Before and after Pneumoperitoneum 5. After release of Pneumoperitoneum 6. After Extubation

Secondary

MeasureTime frame
1Amount of induction agent used 2Post-operative sedation â??Ramsay sedation score â?¢ Post-operative Analgesia-Visual analogue scaleTimepoint: 1min,15min,30min,60min,120min

Countries

India

Contacts

Public Contactshailee shah

SSG HOSPITAL,VADODARA

devyani.dr@gmail.com9909983168

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026