Health Condition 1: null- 1.Coronary angiography demonstrated multivessel coronary artery disease 2.Impaired LV function EFâ?¤35% as documented by Equilibrium Radionuclide Angiography being evaluated for surgery
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Coronary angiography demonstrated multivessel coronary artery disease 2.Impaired LV function EF 3.Informed consent 4.Age >18 years
Exclusion criteria
Exclusion criteria: 1.Acute coronary syndrome 2.NYHA Class III/IV angina 3.Left main coronary artery disease 4.Contraindications to CMR 5.Contraindications to Gadolinium contrast 6.Comorbidities that would likely affect survival over the study duration. 7.Non-cardiac illness imposing substantial operative mortality 8.Already identified to be unsuitable for revascularization 9.Requiring emergency revascularization 10.With severe valvular disease that required surgery. 11.Other conditions/circumstances likely to lead to poor treatment adherence (e.g., history of poor compliance, alcohol or drug dependency, psychiatric illness, no fixed abode)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in 6MWD at 6 months Change in LV function at 6 monthsTimepoint: six months | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome at 6 months and 1 year 1.Composite of death, Myocardial Infarction(as defined by III universal definition of MI), recurrent admission for unstable angina or Heart failure, or repeat revascularization within 1 year 2.6MWD at 1 year 3.Proportion in NYHA class III/IV Timepoint: six months and one year | — |
Countries
India
Contacts
AIIMS New Delhi