Health Condition 1: null- HAVING STABLE VITILIGO ON RESISTANT SITES LIKE ACRAL AREAS AND BONY PROMINENCES. Health Condition 2: L80- Vitiligo
Conditions
Interventions
Intervention1: AUTOLOGOUS MINI PUNCH GRAFTING, SUCTION BLISTER GRAFTING AND NON-CULTURED EPIDERMAL CELL SUSPENSION.: Compare extent of repigmentation after 12 weeks of procedure.
Control Intervention
Sponsors
DEPARTMENT OF DERMATOLOGY
Eligibility
Inclusion criteria
Inclusion criteria: 1. Subjects with clinical diagnosis of focal, segmental or generalized vitiligo. 2. Patients with lesions of size > 1.5cm x 1cm present on acral areas and bony prominences. 3. Vitiligo lesions has been stable for 1 year. 4. Disease not responding to medical treatment or there are residual patches (after medical therapy) of vitiligo which in turn are located on acral areas and bony prominences. 5. Maximum size of vitiligo patches to be selected for surgery will not be >100cm2.
Exclusion criteria
Exclusion criteria: 1) Age less than 18 years 2) Pregnancy and lactation 3) Patient with actively spreading vitiligo 4) History of Koebnerisation 5) History of hypertrophic scars or keloidal tendency 6) Bleeding disorders 7) Patients with unrealistic expectation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the difference in extent of repigmentation by three different methods at 12 weeks of post treatment follow up in a given patient. Timepoint: Follow up will be done on Day 8, then at 4, 8 and 12 weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Pattern of repigmentation attained post-procedure. 2. Color matching of repigmented area. 3. Patient satisfaction (patient global assessment) and quality of life assessement post procedure. 4. Adverse events if any. Timepoint: Follow up will be done on Day 8,then at 4,8 and 12 weeks. | — |
Countries
India
Contacts
Public ContactM SENDHIL KUMARAN
DEPARTMENT OF DERMATOLOGY, POST GRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH, CHANDIGARH.
Outcome results
None listed