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A clinical trial to study the different doses of a drug, Dexmedetomidine and its effect on the pressure changes in the eye caused by another drug,Suxamethonium

A comparative study of different doses of Dexmedetomidine on the effects of intraocular pressure after Suxamethonium in non ocular surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/07/014860
Enrollment
100
Registered
2018-07-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA 1&2

Interventions

Intervention1: Dexmedetomidine: Three different doses of Dexmedetomidine are compared to see which is the optimal dose that attenuates the rise in the intra ocular pressure caused by Suxamethonium Con

Sponsors

Saswati Das
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients willing to participate in the study ASA PS 1&2 Posted for non ophthlamic surgeries Patients with normal intra ocular pressure

Exclusion criteria

Exclusion criteria: Anticipated difficult airway Acute or chronic eye disease Patients with raised intracranial pressure Receiving any drug known to alter intra ocular pressure Pregnant and lactating patients Hypertensive patients taking any anti hypertensives Psychiatric disorders

Design outcomes

Primary

MeasureTime frame
Which of the three doses of Dexmetedomidine decreases the raise in intraocular pressure caused by SuxamethoniumTimepoint: 10 minutes after suxamethonium injection

Secondary

MeasureTime frame
The decrease in duration of the rise in intraocular presseure caused by suxamethoniumTimepoint: 10 minutes after Suxamethonium injection

Countries

India

Contacts

Public ContactSaswati Das

Kalinga Institute of Medical Sciences

das.saswati12@gmail.com9910760328

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026