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Comparison of drug lithium carbonate with escitalopram, for treatment of Depression episode in people with Bipolar Disorder.

The efficacy of Lithium versus Escitalopram , in Acute episode of Bipolar Depression :A Randomized open label trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/07/014858
Enrollment
80
Registered
2018-07-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- BIPOLAR AFFECTIVE DISORDER PATIENTS, IN ACUTE EPISODE OF DEPRESSION

Interventions

Intervention1: oral medication escitalopram 20 to 30mg/day.: antidepressant drug, SSRI group, approved for use by CDSCO, Government of India on January 2003. Drug will be started on 20mg per day, per

Sponsors

ASHA BIPOLAR CLINIC
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. DSM 5 diagnosis of Bipolar Disorder currently in acute episode of Depression. 2. Age between 18 to 65 years 3. To give consent for the study. 4. Bipolar Depression with past mania 5. Bipolar depression on drugs other than trial agents

Exclusion criteria

Exclusion criteria: 1.Ages less than 18 years and more than 65 years; 2. Consent not provided 3. patients who are pregnant. 4. bipolar patients with Mixed episode 5. Anybody who is already on the trial agent

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of oral Escitalopram and lithium carbonate in acute episode of Bipolar Depression, using HAMD scaleTimepoint: 0, 3 weeks and 6 weeks—

Secondary

MeasureTime frame
To compare the side effect profile, functioning level, treatment adherence among both the groups using MOSES, GAF, CRC scale respectivelyTimepoint: 0, 3 weeks, 6 weeks—

Countries

India

Contacts

Public ContactDr Sumati Kumatgi

ASHA HOSPITAL

drmsreddy@gmail.com8008299666

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026